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KMID : 0355420130370040175
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Journal of Korean Academy of Oral Health
2013 Volume.37 No. 4 p.175 ~ p.179
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Polycan-calcium gluconate complex improves gingival health
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Choi Youn-Hee
Kim Ji-Hye
Kim Jae-Young
Lee Young-Kyun
Yang Hae-Young
Song Keun-Bae
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Abstract
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Objectives: The aim of this study was to examine the effect of a Polycan-calcium gluconate complex on gingival health.
Methods: Forty-one subjects with mild periodontitis (≥40 years) were divided into two groups: the placebo and test product (Polycan-calcium gluconate complex twice a day for 4 weeks) groups. Oral examination was performed and gingival crevicular fluid (GCF) was collected from each subject at baseline and after 4 weeks. Interleukin (IL)-1βlevel in the GCF was determined using enzyme-linked immunosorbent assay.
Results: Pocket depth and plaque index were significantly decreased in the test group at 4 weeks. The level of IL-1β and plaque index of the treatment group was significantly lower than of the placebo group.
Conclusions: Based on the above results, Polycan-calcium gluconate complex may inhibit plaque accumulation in the mouth and may have a negative correlation with the level of inflammatory biomarkers. Consequently, gingival health was significantly improved by polycan-calcium gluconate complex.
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KEYWORD
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β-glucan, Calcium gluconate, Gingival health, Polycan
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